
Trying for a Baby? Why AMH Levels Matter
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Numerous elements can influence a woman's likelihood of conceiving. Among these is the level of anti-mullerian hormone (AMH). This hormone, generated by ovarian follicles, serves as a vital marker of ovarian reserve, indicating the remaining quantity of eggs in a woman's ovaries. As infertility rates continue to increase worldwide—impacting one in six individuals, as reported by the World Health Organization (WHO)—the significance of understanding AMH levels has never been more important. This knowledge can offer insights into reproductive health, assisting those who are either preparing for pregnancy or facing challenges with fertility.
What is anti-mullerian hormone (AMH)?
Anti-Müllerian hormone (AMH) is crucial during fetal development, especially in the differentiation of sex organs within the uterus. In male fetuses, elevated levels of AMH inhibit the formation of female reproductive structures. Conversely, females require only minimal amounts of AMH for their reproductive development. This hormone is synthesized by the cells located in the ovarian follicles, which are small, fluid-filled sacs that house and release eggs. In males, AMH is produced by the testes, which are responsible for sperm production and the secretion of male hormones.
AMH levels differ between genders and fluctuate with age. Monitoring these levels can provide valuable insights into reproductive health and fertility. A primary indicator of AMH levels is ovarian reserve, which reflects the quantity of eggs remaining in a woman's ovaries.
- Higher AMH levels indicate a greater number of eggs and a higher ovarian reserve.
- Lower AMH levels suggest fewer eggs and a lower ovarian reserve.

What is an AMH test?
An AMH test is a blood examination that quantifies the level of anti-Müllerian hormone present in the bloodstream. This test is frequently included in fertility assessments, along with various hormone evaluations and imaging studies. For women, the primary purpose of the test is to evaluate ovarian reserve, which indicates the number of viable eggs remaining in the ovaries, as highlighted in research published in the Agricultural and Biological Sciences. It is crucial to understand that while the anti-Müllerian hormone level offers valuable information regarding egg quantity, it does not ensure fertility or the likelihood of conception. Although all individuals produce anti-Müllerian hormone, this test is particularly beneficial for women, as it aids healthcare professionals in assessing their reproductive health and potential for fertility at a specific point in time.
What is a normal AMH level?
Anti-Müllerian hormone (AMH) serves distinct functions in both men and women, with what constitutes a normal AMH level varying based on factors such as sex and age. In females, AMH levels begin to increase during puberty, reaching their highest point in the early 20s, around the age of 25. Subsequently, these levels gradually decrease as women grow older. This reduction is a natural aspect of the aging process, indicating a decline in the ovarian reserve. AMH concentrations are quantified in nanograms per milliliter (ng/mL), and the following outlines the typical ranges of AMH levels across different age groups:
- 45 years old: 0.5 ng/mL
- 40 years old: 1 ng/mL
- 35 years old: 1.5 ng/mL
- 30 years old: 2.5 ng/mL
- 25 years old: 3.0 ng/mL
It is important to note that these results can vary widely. Here's a breakdown of what the numbers generally indicate:
- Normal range: Between 1.0 and 3.0 ng/mL
- Low AMH: Under 1.0 ng/mL
- Severely low AMH: 0.4 ng/mL or lower
- High AMH: Over 4.0 ng/mL
What does an AMH test tell you?
An AMH test is not a clear-cut answer to natural fertility, as it does not predict how easily you can conceive naturally. However, it can provide valuable insights into your reproductive health, particularly in specific contexts.
- If you are healthy and trying to conceive, a high anti-mullerian hormone level suggests you have a larger egg reserve, while a low AMH level means your egg supply is decreasing, which may shorten your window to get pregnant.
- For those undergoing in vitro fertilization (IVF), anti-mullerian hormone is helpful in predicting how many eggs you might produce and in adjusting medication doses to stimulate egg production. It gives an idea of how many eggs remain and whether your ovaries are ageing prematurely. AMH can also help doctors understand how you might respond to fertility medications.
- If you have been tested for polycystic ovary syndrome (PCOS), high AMH levels may indicate the condition, though a diagnosis requires more tests.
- For those approaching menopause, a low AMH level may signal that you are nearing this stage. However, the test cannot tell you exactly when menopause will occur. If no anti-mullerian hormone is detected, it typically means you are in menopause.
- Lastly, in ovarian cancer treatment, a decrease in AMH usually means the treatment is effective. An increase could signal the cancer is returning.

Why do I need an AMH test?
You may need an anti-mullerian hormone test if you are a woman experiencing fertility issues, as it helps assess your egg reserve and determine your response to fertility treatments like IVF. It can also help if you have symptoms of polycystic ovary syndrome (PCOS), such as irregular periods, acne, excessive hair, or weight gain.
Anti-mullerian hormone tests are also used in monitoring ovarian cancer treatment to check if it is effective or if the cancer has returned. In some cases, male children with undescended testicles or ambiguous genitalia may require an AMH test for diagnosis.
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